Noticias

Interesante artículo “Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance”.

septiembre 20, 2021

Abstract Zhou, Karim Lee, Kevin K Leung, Nikolaos Skartsis, Anupurna M Kaul, Arend Mulder, Frans H J Claas, James A Wells, Jeffrey A Bluestone , Qizhi Tang. Front Immunology 2021 Sep 20; 12:686439. 2021 Infusion of regulatory T cells (Tregs) engineered with a chimeric antigen receptor (CAR) targeting donor-derived human leukocyte antigen (HLA) is a promising strategy to promote transplant tolerance. Here, we describe an anti-HLA-A2… Leer más »Interesante artículo “Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance”.

Muy interesante – Prof. Shimon Sakaguchi.

Shimon Sakaguchi is a Professor at the Immunology Frontier Research Center (IFReC) at Osaka University, Japan. He is an immunologist recognized particularly for his discovery of regulatory T cells, an indispensable constituent of the immune system for the maintenance of immune self-tolerance and homeostasis. Sakaguchi obtained an M.D. in 1976 and a Ph.D. in 1982… Leer más »Muy interesante – Prof. Shimon Sakaguchi.

Interesante artículo “Immune Monitoring for Advanced Cell Therapy Trials in Transplantation: Which Assays and When?”

marzo 25, 2021

See this image and copyright information in PMC Helen L Stark, Hayson C Wang, Jasmina Kuburic, Alaa Alzhrani, Joanna Hester, Fadi Issa. Front Immunol. 2021 Mar 25;12:664244.  DOI: 10.3389/fimmu.2021.664244 Abstract A number of immune regulatory cellular therapies, including regulatory T cells and mesenchymal stromal cells, have emerged as novel alternative therapies for the control of transplant alloresponses. Clinical studies have demonstrated their… Leer más »Interesante artículo “Immune Monitoring for Advanced Cell Therapy Trials in Transplantation: Which Assays and When?”